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Symbol Name ID |
Hif1a
hypoxia inducible factor 1, alpha subunit MGI:106918 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal blood vessel morphology |
abnormal dorsal aorta morphology |
dilated dorsal aorta |
absent pharyngeal arch arteries |
pharyngeal arch artery hypoplasia |
abnormal brain vasculature morphology |
abnormal intersomitic vessel morphology |
abnormal vascular development |
abnormal angiogenesis |
abnormal vascular regression |
decreased angiogenesis |
abnormal vascular endothelial cell migration |
disorganized yolk sac vascular plexus |
abnormal myocardium layer morphology |
abnormal myocardial trabeculae morphology |
absent myocardial trabeculae |
disorganized myocardium |
abnormal cardiac outflow tract development |
abnormal heart development |
abnormal heart looping |
abnormal heart tube morphology |
cardia bifida |
abnormal coronary vessel morphology |
thick interventricular septum |
abnormal heart size |
cardiac hypertrophy |
abnormal heart ventricle morphology |
abnormal heart left ventricle morphology |
increased heart left ventricle weight |
increased heart left ventricle wall thickness |
abnormal pericardial cavity morphology |
abnormal pericardium morphology |
pericardial effusion |
abnormal cardiovascular system physiology |
decreased cardiac muscle contractility |
abnormal cardiac muscle relaxation |
abnormal heart left ventricle pressure |
abnormal myocardial fiber physiology |
abnormal systemic arterial blood pressure |
decreased vascular endothelial cell proliferation |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||
| Hif1atm1Jhu/Hif1atm1Jhu | ||||||||||||||||||||||||||||||||||||||||||
| Hif1atm1Pec/Hif1atm1Pec | ||||||||||||||||||||||||||||||||||||||||||
| Hif1atm1Rsjo/Hif1atm1Rsjo | ||||||||||||||||||||||||||||||||||||||||||
| Hif1atm2Rsjo/Hif1atm2Rsjo | ||||||||||||||||||||||||||||||||||||||||||
| Hif1atm1Stom/Hif1atm1Stom A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Col2a1-cre)1Rsjo/? (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(MMTV-cre)1Mam/0 (conditional) |
* | |||||||||||||||||||||||||||||||||||||||||
| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Tek-cre)1Ywa/0 (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Myl2tm1(cre)Krc/Myl2+ (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Camk2a-cre)1Szi/0 (conditional) |
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| Hif1atm1Rsjo/Hif1atm3Rsjo Tg(Col2a1-cre)1Rsjo/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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